MyBioSource.com's HBG1 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The HBG1 Antibody (Center) was generated using HBG1 as the antigen and it reacts with Human.
Description
The gamma globin genes (HBG1 and HBG2) are normally
expressed in the fetal liver, spleen and bone marrow. Two gamma
chains together with two alpha chains constitute fetal hemoglobin
(HbF) which is normally replaced by adult hemoglobin (HbA) at
birth. In some beta-thalassemias and related conditions, gamma
chain production continues into adulthood. The two types of gamma
chains differ at residue 136 where glycine is found in the G-gamma
product (HBG2) and alanine is found in the A-gamma product (HBG1).
The former is predominant at birth. The order of the genes in the
beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta
-- beta--3'